Contract manufacturing

In Budapest, at the main production site in Keresztúri Street, we produce intermediates and active pharmaceutical ingredients with organic chemical synthesis on large-scale production lines and in several production halls.

Our manufacturing processes and activities fully comply with cGMP principles.

Our facility has successfully undergone comprehensive audits and received accreditation from key regulatory authorities, including FDA (USA) (first in 1976), EDQM (EU), PMDA (Japan), KFDA (South Korea), ANVISA (Brazil).

Thanks to its technology upgrading investments, Egis is able to produce faster, more efficiently and at lower costs, even in small batches, and can produce a wide range of active pharmaceutical ingredients.

Recipe-controlled production lines with fully automated process control systems enable safe operation, with lower energy consumption and lower CO2 emissions. From an operational point of view, one of the most significant advantages is that our production lines are multifunctional, i.e. they are capable of producing several types of active pharmaceutical ingredients, and they can be switched from one product to another flexibly and in a very short time.

Our services: 

Chemical reactions

  • Aminolysis
  • Amination (with NH3, or reduction)
  • Grignard reaction
  • Alkylation
  • Etherification
  • Nitration
  • Nitrosation
  • Acylation
  • sterification
  • Friedel-Crafts reaction
  • Mannich reaction
  • Hydrolysis
  • Chiral resolution
  • Reduction using sodium
  • borohydride and lithium aluminium hydride
  • Methylation with dimethyl sulfate
  • Chlorination
  • Hofmann rearrangement
  • Vilsmeier reaction
  • Hydrogenation
    • Disulfide bond cleavage
    • Enantioselective hydrogenation of the C=C double bond
    • Reductive amination of a carbonyl group
    • Hydrogen addition to an imine double bond
    • Saturation of the interchain C=C triple bond
    • Reduction of N-nitroso group to N-amine
    • Reduction of aromatic nitro group to amine
    • Condensed ring aromatization
    • Hydrogenation of a nitrile group to an amino group
    • Partial saturation of a N-heterocycle partial saturation
    • Reduction of esters
    • Reduction of a carbonyl group
  • Knoevenagel condensation
  • Eschweiler–Clarke reaction
  • Lithiation
  • Specialities
    • Tantalum-coated reactor, for highly acidic reactions under high pressure
    • Short path three-stage distillation apparatus
    • Incineration

Equipment

  • Reactor lines from 630 to 10.000 L
  • Catalytic hydrogenation capabilities
    • 2.000 L, 50 bar, 100 °C
    • 2 x 2.500 L, 2 x 1.600 L, 6 bar, 100 °C
    • 250 L, 20 bar, 100 °C
  • Clean area
    • Tray dryers, vacuum dryers, fluid bed dryer, double cone dryer, paddle type dryer
    • Hammer mills, pin mills, micronizing equipment, various powder handling systems

Contact us at pharmaservices@egis.hu or fill the form below.
 

Egis Pharma Service - Contact us!

 Click here to subscribe to our newletter!

 

 

Cookie Settings

Egis’s website uses cookies to run our website, improve the user experience and monitor the activities. You can customize the use of the cookies by adapting the settings.

Cookies necessary for basic functioning

These cookies ensure the appropriate functioning of the website, facilitate its use and collect information on its use without identifying visitors.

Functional cookies

In order to enhance the user experience, we use cookies which record the use of certain functions of the website, thus enabling users to have the same settings at the time of their next visit.

Cookies for statistical purposes

They provide statistical data on the performance of the website (such as number of page loads, average time spent on the website) in order to collect data for the operator of the website on the website usage patterns of users. These cookies do not identify visitors, information collected by them relate to the number of subpages visited by the user, the length of each session, the types of error messages, etc. Cookies for statistical purposes are automatically placed on the user’s devices during browsing, and you can delete such cookies in the browser settings.
Details
I Agree
WarningYour browser is out of date. Please, use an updated version! Chrome || Firefox